Cyclica

Cyclica is a technology company that improves drug discovery/development by reducing complex Big Data into high utility insights through its proprietary technology, Ligand Express™. Ligand Express™ uses an integrated systems approach to index the entire proteome. The platform annotates molecules to their basic building blocks to test and model a drug’s impact on all aspects of human biology. Analysis of these building blocks reveals consistent drug-protein interactions, which are indexed based upon their patterns. These pre-clinical insights will improve current attrition rates of lead therapeutic compounds, and improve patient outcomes with fewer side effects. Through a partnership with IBM, Cyclica is creating vast stores of pre-computed data that is useful for analyzing cross reactivity of molecules to assess safety and efficacy. As such, Cyclica risk adjusts development pipelines, and provides its clients with actionable analysis to help guide their development strategies.